Prevention program results in weight loss in patients with CAD

August 19, 2021

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A comprehensive secondary prevention program achieved significantly increased rates of weight loss in obese patients with CHD, researchers in Heart reported.

Previously, researchers evaluated this weight loss program as a comprehensive secondary prevention strategy in the multicenter randomized RESPONSE-2 study and found that a combination of nurse-coordinated care and referral to up to three community-based lifestyle programs in addition to usual care was significantly more effective at that Improvement of at least one lifestyle-related risk factor compared to conventional treatment.

Weight loss scale and tape measure 2019

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“The lifestyle programs focused on weight loss, physical activity promotion and smoking cessation, and referral was dependent on the risk profile and patient preferences.” Arno Tijssen, clinical epidemiologist and alternative practitioner at the competence center and health faculty of the Amsterdam University of Applied Sciences, and colleagues wrote. “The difference in the primary endpoint was mainly caused by improvements in weight loss.”

This secondary analysis used data from a subset of CHD patients who were overweight and had a BMI of at least 27 kg / m2 from the RESPONSE-2 study. The patients were randomly assigned to intervention plus standard care (n = 280) or standard care alone (n = 257). The researchers assessed the change in weight from baseline up to 12 months during follow-up.

Significantly more weight loss was observed in the patients in the intervention group compared to the controls, with an average loss of –2.4 kg vs. –0.2 kg (P

The researchers observed that a weight loss of at least 5% with older age (OR = 2.94; 95% CI 1.57-5.48; P

“Terrifyingly, weight gain has been widespread, and preventing it from gaining weight can be just as important as trying to lose weight,” the researchers wrote. “The identified determinants of weight change can contribute to the further development of effective weight management strategies.”

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